Lingfeng He Selected Research

Flap Endonucleases

1/2020	MicroRNA-140 impedes DNA repair by targeting FEN1 and enhances chemotherapeutic response in breast cancer.
12/2019	Inhibition of AKT Sensitizes Cancer Cells to Antineoplastic Drugs by Downregulating Flap Endonuclease 1.
4/2017	Interacting partners of FEN1 and its role in the development of anticancer therapeutics.
1/2017	FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer.
12/2016	Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression.

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Lingfeng He Research Topics

Disease

21	Neoplasms (Cancer) 01/2022 - 07/2005
4	Breast Neoplasms (Breast Cancer) 01/2022 - 03/2013
4	Genomic Instability 01/2020 - 01/2016
3	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 04/2006
3	Lung Neoplasms (Lung Cancer) 12/2019 - 06/2010
2	Carcinogenesis 01/2020 - 05/2019
2	Neoplasm Metastasis (Metastasis) 01/2020 - 05/2019
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 01/2017
2	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 03/2013
1	Bites and Stings (Sting) 07/2022
1	Hemangioma (Angioma) 01/2022
1	Pathologic Processes 01/2022
1	Wounds and Injuries (Trauma) 10/2021
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Colonic Neoplasms (Colon Cancer) 01/2020
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 10/2019
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2018
1	Hypercholesterolemia 08/2015
1	Melanoma (Melanoma, Malignant) 07/2005

Drug/Important Bio-Agent (IBA)

5	Pharmaceutical PreparationsIBA 10/2022 - 01/2018
5	Flap EndonucleasesIBA 01/2020 - 12/2016
4	Cisplatin (Platino)FDA LinkGeneric 12/2019 - 01/2017
3	Antineoplastic Agents (Antineoplastics)IBA 01/2021 - 01/2018
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 12/2016
2	CamptothecinIBA 01/2022 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2018
2	Fluorouracil (Carac)FDA LinkGeneric 01/2020 - 01/2018
2	Arginine (L-Arginine)FDA Link 05/2019 - 01/2016
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018 - 09/2012
1	Temozolomide (Temodar)FDA LinkGeneric 10/2022
1	Peptide LibraryIBA 10/2022
1	Interleukin-1 (Interleukin 1)IBA 07/2022
1	Interleukin-18 (Interleukin 18)IBA 07/2022
1	Biological ProductsIBA 01/2022
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2022
1	Epidermal Growth Factor (EGF)IBA 01/2022
1	N-methyladenosineIBA 01/2022
1	MethyltransferasesIBA 01/2022
1	Propranolol (Inderal)FDA LinkGeneric 01/2022
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2020
1	DNA Polymerase beta (DNA Polymerase IV)IBA 01/2020
1	3' Untranslated Regions (3' UTR)IBA 01/2020
1	Histones (Histone)IBA 05/2019
1	TransferasesIBA 09/2018
1	Histone DemethylasesIBA 09/2018
1	Carboplatin (JM8)FDA LinkGeneric 01/2018
1	Checkpoint Kinase 1IBA 01/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2018
1	Biomarkers (Surrogate Marker)IBA 04/2017
1	Therapeutic UsesIBA 01/2017
1	A-Form DNA (A-DNA)IBA 01/2017
1	LGK974IBA 01/2016
1	Glutamine (L-Glutamine)FDA Link 01/2016
1	Amino Acids FDA Link 01/2016
1	SOX9 Transcription FactorIBA 01/2016
1	oxidized low density lipoproteinIBA 08/2015
1	LDL Receptors (LDL Receptor)IBA 08/2015
1	LDL CholesterolIBA 08/2015
1	Proprotein Convertase 9IBA 08/2015
1	Androgen Receptors (Androgen Receptor)IBA 03/2013
1	AndrogensIBA 03/2013
1	Proto-Oncogene Proteins c-etsIBA 03/2013
1	CateninsIBA 03/2013
1	Transcription Factor 7-Like 2 ProteinIBA 03/2013
1	Low Density Lipoprotein Receptor-Related Protein-6IBA 03/2013
1	InterferonsIBA 09/2012
1	EnzymesIBA 06/2010
1	Interferon-betaIBA 06/2010
1	ImmunosorbentsIBA 06/2010
1	Superoxide DismutaseIBA 04/2006
1	LigandsIBA 04/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2006
1	Caspase 9IBA 07/2005
1	dl1520 (ONYX-015)IBA 07/2005
1	Caspase 3 (Caspase-3)IBA 07/2005
1	InterleukinsIBA 07/2005

Therapy/Procedure

12	Therapeutics 01/2022 - 07/2005
4	Drug Therapy (Chemotherapy) 10/2022 - 01/2017
1	Sutures (Suture) 10/2021